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KMID : 0061119810090000112
Bulletin of the Clinical Research Institute
1981 Volume.9 No. 0 p.112 ~ p.112
The Changes of Cardiopulmonary Function and Somatosensory Evoked potentials in Experimental Cerebral Missile Injury and the Effect of Mannitol
Kim, Moon-Chan
Kim, Dal-Soo/Ha, Young-Soo/Kang, Joon-Ki/Song, Jin-Un
Abstract
potential (SEP) were studied in 40 cats before and after a right occipito-frontal missile in-jury with an air rifle. The sensory evoked potential was present shortly after injury through markedly altered in shape.
There was a very close correlation between somatoevoked potential and cerebral damage on the injured side, and the amplitude was much smaller, perhaps due to direct injury. The late component of sensory evoked potential was severely suppressed possibly due to functionally interruped brain stem multisynaptic pathway.
The early components of sensory ;evoked potential have recovered nearly to normal range after 30 minutes in mannitol treated.
This suggests that the specific somatosensory pathways are most vulnerable to high kinetic missile injury.
The late component of SEP (N2) was easily and severely suppressed possibly due to functionally interrupted brain-stern multisynaptic pathway and almost not recovered.
At an intracranial pressure (ICP) of 29 cmH_(2)O, the early components (No, NI) of SEP were significantly suppressed to 80% of the normal control.
At the ICP higher than 40 cmH_(2) not only the N2 appeared flat, but also No and N1 were suppressed. The early components (No, NI) of SEP have recovered nearly to normal range after 30 minutes in the mannitol treated group, however, late N2 component was almost not recovered.
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